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      Lumbo-sacral pain syndrome — a contemporary perspective with soft-tissue mechanisms

      Written by Pawel Borowinski

      In the lumbo-sacral region, clinicians frequently encounter:

      • Degenerative changes of intervertebral discs and facet joints

      • Irritation or overload of the sacroiliac joints

      • Inflammatory and rheumatic conditions

      • Acute episodes of “lumbago"

      Pain may appear gradually or suddenly and is commonly accompanied by a protective muscular spasm, which immobilizes the segment but also increases stiffness and limitation of movement.

      Predisposing factors include:

      • Obesity and low physical activity

      • Pregnancy

      • Limb-length discrepanc,

      • Sudden, uncontrolled movement

      • Prolonged sitting

      • Chronic stress and elevated muscle tone

      Current literature emphasizes that — beyond discs and joints — the myofascial system (muscles, fascia, entheses and connective tissue interfaces) represents a major generator of lumbar pain.

      Myofascial component: taut bands, myogelosis and fascial pain

      Taut bands and myogelosis

      Within overloaded lumbar and pelvic muscles, clinicians often palpate taut bands — dense, cord-like strands of muscle fibers.

      They are typically associated with:

      • Local tissue thickening

      • Marked tenderness

      • Reduced elasticity

      • Referred pain patterns

      Within these taut bands, myofascial trigger points may develop, producing:

      • Localized lumbar pain

      • Pain radiating to the buttock or posterior thigh

      • A sensation of “rigidity” across the lower back

      In classical terminology, this corresponds to myogelosis — chronic nodular thickening of muscle associated with microcirculatory disturbance and persistent tension.

      Fascial and connective-tissue pain — including night-time awakening

      The thoracolumbar fascia and surrounding connective tissues form a continuous tension network connecting the pelvis, spine and rib cage.

      Fascial dysfunction may involve:

      • Adhesions and thickening

      • Loss of inter-layer gliding

      • Altered hydration of the extracellular matrix

      • Increased mechanosensiS

      These changes can result in:

      • Persistent interscapular and lumbar discomfort

      • “Tightness” across the lower back

      • Disturbed breathing mechanics and trunk mobility

      • Compensatory loading of the cervical and lumbar segments

      Because fascia is richly innervated, overload can maintain and perpetuate pain, often independently of structural imaging findings.

      Clinically, fascial or connective-tissue pain may:

      • Intensify in the evening

      • Awaken the patient during the night

      • Present with morning stiffness after prolonged immobility

      • Worsen when changing position in bed

      • Sharp “blocking” pain and so-called piezo-active points

      In many cases, patients report sudden, sharp, movement-stopping (“blocking”) pain, occurring during the last degrees of bending, rotation or extension.

      These episodes are thought to arise from highly mechanosensitive structures:

      • Ligamentous attachments (entheses)

      • Joint capsules

      • Periosteum

      • Fascia

      On the cellular level, increasing attention has been paid to mechanosensitive ion channels (such as Piezo1 and Piezo2), which:

      • Respond to stretch and deformation

      • Modulate calcium influx

      • Participate in mechanonociception and inflammatory signaling

      clinically, “piezo-active points” may be understood as zones where mechanical load triggers a sudden, sharp protective pain — despite the absence of major structural lesions on imaging.

      Pain character as a diagnostic clue. Mechanical pain (discs, joints, muscles, fascia, ligaments):

      • Increases with overload and prolonged static positions

      • Often improves with gentle movement

      • Is accompanied by stiffness or a pulling sensation in the tissues

      • Neurogenic / dural / central pain

      • May be less dependent on posture

      • May worsen at night

      • Can be accompanied by neurologic signs: numbness, weakness, altered reflexes

      1) Localized, piercing (sharp) pain commonly linked to:

      • Facet joints

      • Sacroiliac joints

      • Irritated entheses or “piezo-active” zones

      • Pain is clearly localized and movement-dependent

      2) Chronic lumbar pain may be dull or sharp, intermittent or constant, and often coexists with:

      • Osteoarthritis or osteoporosis

      • Degenerative disc disease

      • Myofascial overload

      • Postural dysfunction

      • Central sensitization

      Soft-tissue injury - local damage to muscle fibers, ligaments or tendons
      — acute, well-localized pain with several days of stiffness.

      Loss of motion with “locking” sensation - sudden movement may provoke joint restriction and reflex muscle guarding.

      Excessive muscle tension - palpable taut bands, myogelotic nodules and tender trigger areas maintaining a protective spasm.

      Nocturnal fascial / connective-tissue pain = night awakening, increased discomfort when changing position, and morning stiffness related to prolonged immobility and reduced tissue lubrication.

      Key clinical insights:

      • Lumbo-sacral pain is typically multifactorial

      • Imaging findings do not always explain symptoms

      • Soft tissues (muscles, fascia, entheses) are major contributors

      • Taut bands, piezo-sensitive zones and fascial dysfunction can strongly modulate pain perception

      • Night pain may reflect connective-tissue and fascial involvement rather than purely spinal pathology

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